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Dr. Chaofeng Zhang is an associate professor at Department of Biological & Pharmaceutical Engineering, College of Biomedical Engineering, Taiyuan University of Technology, Taiyuan 030024, PR China. E-mail: zhangchaofeng@tyut.edu.cn Website: http://tylgswyxgc.tyut.edu.cn/info/1049/1240.htm |
Education
2004-2007 |
Shanxi University, China |
Inorganic Chemistry |
Ph.D. |
2001-2004 |
Shanxi University, China |
Inorganic Chemistry |
Master |
1992-1996 |
Shanxi Normal University, China |
Chemistry |
Bachelor |
Professional Experience
2007-now |
|
Taiyuan University of Technology, China |
2015-2016 |
|
Simon Fraser University, Canada |
Research interests
- Design, synthesis of drugs for the treatment of Alzheimer’s Disease
- Metal-Organic Frameworks in biomedicine
Publications
> 30 articles and 10 patents
Selected publications
1. Chaofeng Zhang, Yaozong Yang, Linfeng Li, Jiandong Zhang, Shuangping Huang, Ruifeng Li*, Ionic Liquid Encapsulated in MIL-100 (Fe): A Green Catalyst for Synthesis of Polyoxymethylene Dimethyl Ethers from Methanol and Trioxane, Ind Eng Chem Res, 2020, 59: 17094-17012
2. Chaofeng Zhang*, Tonglu Zhang, Jing Zhang, Jiandong Zhang, Ruifeng Li, Controllable synthesis of polyoxymethylene dimethyl ethers by ionic liquids encapsulated in mesoporous SBA-16, Chinse J Chem Eng, 2020, https://doi.org/10.1016/j.cjche.2020.09.016
3. Chaofeng Zhang*, Luiza M.F. Gomes, Tonglu Zhang, and Tim Storr*, A small bifunctional chelator that modulates Aβ42 aggregation, Can J Chem., 2018, 96: 78-82,
4. Jian-Dong Zhang*, Hua-Lei Wu, Tong Meng, Chao-Feng Zhang**, Xiao-Jun Fan, Hong-Hong Chang, Wen-Long Wei. A high-throughput microtiter plate assay for the discovery of active and enantioselective amino alcohol-specific transaminases, Anal Biochem, 2017, 518: 94-101
5. Hua-Lei Wu, Jian-Dong Zhang, Chao-Feng Zhang, Xiao-Jun Fan, Hong-Hong Chang, Wen-Long Wei. Characterization of Four New Distinct ω-Transaminases from Pseudomonas putida NBRC 14164 for Kinetic Resolution of Racemic Amines and Amino Alcohols, Appl Biochem Biotechnol, 2017, 181:972-985
6. Chao-Feng Zhang, Shao-Jin Han,Yan-Bo Wu, Hai-Gang Lu, Gang Lu. Thermodynamic Stability versus Kinetic Stability: Is the Planar Hexacoordinate Carbon Species D3h CN3Mg3+ Viable? J Phys Chem A, 2014, 118: 3319 -3325
7. Chaofeng Zhang, Li Fan, Pin Yang. Study of the interaction of Zn2+ with Aβ (10-21) by fluorescamine assay. Chinese Chem Lett, 2007, 18: 97-98
8. Yue-Jun Fu, Li-Tian Yin, Ai-Hua Liang, Chao-Feng Zhang, Wei Wang, Bao-Feng Chai, J.Y. Yang, Xiao-Jun Fan. Therapeutic potential of chlorotoxin-like neurotoxin from the Chinese scorpion for human gliomas. Neursci Lett, 2007, 412: 62-67
9. Chaofeng Zhang, Li Fan, Pin Yang. Study of the interaction of unaggregated and aggregated amyloid β protein (10-21) with outward potassium channel, Sci China Ser B, 2007, 50(5): 683-691
10. Hui-Zhi Du，Chao-Feng Zhang，Miao-Yu Li，Pin Yang. 3-benzidino-6 (4-chlorophenyl) pyridazine blocks delayed rectifier and transient outward potassium current in acutely isolated rat hippocampal pyramidal neurons. Neurosci Lett, 2006, 402: 159-163
11. Chao-Feng Zhang, Pin Yang. Zinc-induced aggregation of Aβ (10-21) potentiates its action on voltage-gated potassium channel. Biochem Biophys Res Co, 2006, 345: 43-49
12. Zhang Chaofeng, Du Huizhi, Yang Pin, Ion Channel Hypothesis for Molecular Mechanism of Alzheimer’s Disease, Prog Chem, 2006, 18 (9): 1194-1199
13. Chaofeng Zhang，Huizhi Du, Pin Yang. Effects of lithium chloride on outward potassium currents in acutely isolated hippocampal CA1 pyramidal neurons. Chinese Sci Bull, 2006, 51(16): 1961-1966
14. Chaofeng Zhang, Pin Yang, Shaowu Xue. Study of magnesium effects on slow vacuolar ion channel in radish by patch-clamp technique. Acta Chim Sinica. 2005, 63 (12): 1147-1150
Patents
1. Zhang, C.; Li, J.; Zhang, T.; Yang, Y.; Li, R. China Patent CN 107626346 B, 2020.
2. Li, R..; Zhang, C.; Li, J.; Zhang, T.; Yang, Y. China Patent CN 107694603 B, 2020.
3. Li, Y.; Wan, L.; Xing, J.; Liu, Q.; Zhang, C.; Chang,H. ; Li, X.; Wei, W. China Patent CN 106501412 B, 2019.
4. Li, Y.; Xing, J.; Wang, L.; Zhang, Z.; Zhang,C.; Chang, H.; Li, X.; Wei, W. China Patent CN 104177328 B, 2016.
5. Zhang, C.; Xing, J.; Liu, K.; Zhu, Z.; Wang, J.; Li, R. China Patent CN 103381373 B, 2016.
6. Zhang, C.; Li, J.; Chen, S.; Zhang, H.; Zhu, Z.; Wang, J.; Li, R. China Patent CN 103381372 B, 2015.
7. Xing, J.; Zhang, C.; Zhang, Z.; Li, Y.; Wei, W.; Chang, H., Li, X. China Patent CN 103288795 B, 2014.
8. Zhang, C.; Li, X.; Zhang, F. ;Chang, H. China Patent CN 102875428 B, 2014.
9. Zhang, C.; Li, X.; Zhang, F. ; Chang, H. China Patent CN 102875421 B, 2014.
Awards
1. Second Prize of Teaching Achievement Award of Taiyuan University of Technology, 2019.
2. Second Prize of Natural Science of Shanxi Science and Technology Award, 2010,
