 Dr.Xiaolu Ma is a professor at Department of Biomedical Engineering, Taiyuan University of Technology, Taiyuan 030024, PR China.
E-mail: maxiaolu@tyut.edu.cn |
Education
2011-2017 |
University of Chinese Academy of Sciences, China |
Biochemistry and Molecular Biology |
Ph.D. |
2007-2011 |
Northwest Agriculture & Forest University , China |
Biotechnology |
Bachelor |
Professional Experience
2018-now |
|
Taiyuan University of Technology, China |
Research interests
- Genome instability and tumor chemo-resistance
- Mechanobiology related to human diseases
Publications
>10 articles
Selected publications
1. Ma X, Tang TS, Guo C. “Regulation of translesion DNA synthesis in mammalian cells”. Environ Mol Mutagen. 2020 Aug;61(7):680-692. doi: 10.1002/em.22359. Epub 2020 Feb 6. PMID: 31983077. (IF: 3.131)
2. Ma X#, Liu H#, Li J#, Wang Y, Ding Y, Shen H, Yang Y, Sun C, Huang M, Tu Y, Liu Y, Zhao Y, Dong M, Xu P, Tang T*, Guo C*. “Polη O-GlcNAcylation governs genome integrity during translesion DNA synthesis”. Nature Communications 8, 1941 (2017). doi:10.1038/s41467-017-02164-1. (IF: 12.123)
3. Zhu X#, Ma X#, Tu Y#, Huang M, Liu H, Wang F, Gong J, Wang J, Li X, Chen Q, Shen H, Zhu S, Wang Y, Liu Y, Guo C*, Tang T*. “Parkin regulates translesion DNA synthesis in response to UV radiation”. Oncotarget. 2017 Apr 05. doi: 10.18632/oncotarget.16855. (IF: 5.168)
4. Wang K#, Ma X#, Zhang X, Wu D, Sun C, Sun Y, Lv X, Wu C*, Guo C*, Ruan J*. “Using ultra-sensitive next generation sequencing to dissect DNA damage-induced mutagenesis”. Scientific Reports, 2016 Apr 28;6:25310. doi: 10.1038/srep25310. (IF:4.269)
5. Gong J#, Huang M#, Wang F#, Ma X, Liu H, Tu Y, Xing L, Zhu X, Zheng H, Fang J, Li X, Wang Q, Wang J, Sun Z, Wang X, Wang Y, Guo C, Tang TS. “RBM45 competes with HDAC1 for binding to FUS in response to DNA damage”. Nucleic Acids Research, 2017 Nov 13. doi: 10.1093/nar/gkx1102.
6. Tu Y#, Liu H#, Zhu X#, Shen H, Ma X, Wang F, Huang M, Gong J, Li X, Wang Y, Guo C*, Tang TS*. “Ataxin-3 promotes genome integrity by stabilizing Chk1”. Nucleic Acids Research, 2017 May 5;45(8):4532-4549. doi: 10.1093/nar/gkx095.
7. Liu H#, Li X#, Ning G#, Zhu S#, Ma X, Liu X, Liu C, Huang M, Schmitt I, Wüllner U, Niu Y, Guo C*, Wang Q*, Tang TS*. “The Machado-Joseph Disease Deubiquitinase Ataxin-3 Regulates the Stability and Apoptotic Function of p53”. PLOS Biology, 2016 Nov 16;14(11):e2000733.
8. Liu Y, Ma X, Guo C*. “Effects of the N terminus of mouse DNA polymerase κ on the bypass of a guanine-benzo[a]pyrenyl adduct”. The Journal of Biochemistry, 2016 Apr;159(4):471-9. doi: 10.1093/jb/mvv118.
9. Wang Z, Huang M, Ma X, Li H, Tang T*, Guo C*. “REV1 promotes PCNA monoubiquitination through interacting with ubiquitinated RAD18”. Journal of Cell Science, 2016 Mar 15;129(6):1223-33.
10. Yang Y#, Liu Z#, Wang F#, Temviriyanukul P#, Ma X, Tu Y, Lv L, Lin YF, Huang M, Zhang T, Pei H, Chen BP, Jansen JG, de Wind N, Fischhaber PL, Friedberg EC, Tang TS*, Guo C. “FANCD2 and REV1 cooperate in the protection of nascent DNA strands in response to replication stress”. Nucleic Acids Research, 2015 Sep 30;43(17):8325-39.
Awards and Honors
Shanxi Provincial "Sanjin Talents” Support Program for Young Excellent Talents, 2018
Projects
National Nature Science Foundation of China for Youths ( No. 31800684), 2019.01-2021.12.
Shanxi Province Natural Science Foundation for Youths (No. 201801D221281) ,2018.12-2020.12.
