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Dr. Shuangping Huang is an associate professor at Department of Biological and Pharmaceutical Engineering, College of Biomedical Engineering, Taiyuan University of Technology, Taiyuan 030024, PR China E-mail: hsping02@gamil.com Website: http://tylgswyxgc.tyut.edu.cn/info/1049/1217.htm |
Education
2006-2012 |
Peking University, China |
Organic Chemistry |
Ph. D |
2002-2006 |
Tianjin University, China |
Pharmaceutical Engineering |
Bachelor |
Professional Experience
2018-now |
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Taiyuan University of Technology, China |
2012-2018 |
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Jiangxi Science and Technology Normal University, China |
Research interests
- Synthesis and Structure-activity relationship study of natural products with biological activity
Recent work related to some topics in natural products, mainly focused on total synthesis of some natural products with novel biological activity, and their analogues and derivatives, such as alkaloid, steroid and diterpenoid. Interests are also including the structure-activity relationship study of these natural products through the test of their biological activity.
Publications
> 20 articles and 4 patents.
Selected publications
1. Yiying Pang, HeshengXiao, WentaoOu, XuesongZhang, XiaojiWang*, ShuangpingHuang*. A concise total synthesis of (−)-γ-lycorane via an aromatic C-H alkylation of unactivated secondary alkyl iodide. Tetrahedron Lett. 2020, 61, 151733.
2. ShuangpingHuang, WentaoOu, WangLi, HeshengXiao, YiyingPang, YiZhou, XiaojiWang*, XihuaYang*, LipingWang*. A total synthesis of (+)-brazilin. Tetrahedron Lett. 2020, 61, 152052.
3. Xiaoji Wang, Yi Zhou, Hesheng Xiao, Wentao Ou, Yiying Pang, Wang Li, Liping Wang*. Shuangping Huang*. Formal Synthesis of (±)-Aplykurodinone-1 Based on the Indium-Catalyzed Conia-ene Reaction. Synlett. 2020, 31, 748-752.
4. Jiwu Wang, Wang Li, Lixia Liu, Bo Wang, Yi Zhou, Shuangping Huang*, Xiaoji Wang*. A unified and straightforward total synthesis of (+)-porantheridine and (-)- 6-epi-porantheridine, Org. Chem. Front. 2019, 6, 1599-1602.
5. Ying Peng, Yongli Sun, Bo Wang, Yi Zhou, Shuangping Huang*, Xiaoji Wang*. Formal synthesis of (±)-aplykurodinone-1 through an intramolecular Michael addition, Tetrahedron Lett. 2019, 60, 839-842.
6. Lixia Liu, Yongli Sun, Jiwu Wang, Wentao Ou, Xiaoji Wang*, Shuangping Huang*. A New Formal Synthetic Route to Entecavir, Synlett. 2019, 30, 748-752.
7. Bo Wang, Liping Wang, Ying Peng, Yiying Pang, Hesheng Xiao, Xiaoji Wang*, Shuangping Huang*. Molecules, 2019, 24, 999.
8. Xiaotong Li, Gaopeng Wang, Zhibin Zhang, Na Wu, Qianqian Yang, Shuangping Huang*, and Xiaoji Wang*. A concise and straightforward approach to total synthesis of (+)-Strictifolione and formal synthesis of Cryptofolione via a unified strategy. Synthetic Commun. 2019, 8, 1031-1039.
9. Bo Qiu, Xiao-Tong Li, Jian-Yu Zhang, Jun-Ling Zhan, Shuang-ping Huang, Tao Xu*. Catalytic Enantioselective Synthesis of 3,4-Polyfused Oxindoles with Quaternary All-Carbon Stereocenters: A Rh-Catalyzed CC Activation Approach, Org. Lett. 2018, 20, 7689-7693.
10. Junrong Huang, Wenli Bao, Shuangping Huang, Wei Yang, Zhu Lizhi, Guangyan Du*, Chi-Sing Lee*. Formal Synthesis of (+)-Phomactin A, Org. Lett. 2018, 20, 7466−7469
11. Zhibin Zhang, Xiao Leng, Shenkun Yang, Cheng Liang, Shuangping Huang*; Xiaoji Wang*. A novel totalsynthesis of aculeatin A via a stepwise approach. RSC Adv. 2017, 7, 9813-9818.
